How to choose Mechanical Homogenizers
Mechanical homogenizers typically refer to devices that apply direct high-speed mechanical action—such as rotor-stator systems or bead-beating mechanisms—to shear, impact, and grind samples. They are suitable for materials with high viscosity or high solid content.
Mechanical Shear Force
Mechanical shear force refers to a pair of equal, opposite, and nearly parallel forces whose lines of action are very close. When applied to a material, they induce internal sliding, tearing, or deformation. Shear force is mainly generated through velocity gradients and narrow gaps within the homogenizing mechanism.
Classification of Mechanical Homogenizers
High-Shear Homogenizer
Rotor
The high-speed rotating component, typically driven by a shaft and shaped like a toothed turbine or impeller. It is the active working part. Through rapid rotation, it generates strong centrifugal forces that draw in, accelerate, and propel the material.
Stator
The stationary component that tightly surrounds the rotor, usually with teeth or perforations. It acts as a passive “anvil” and “sieve.” Together with the rotor, it forms an extremely narrow gap that subjects the fast-flowing material to shear, compression, and fragmentation.
Power
550 W / 710 W
160 W / 200 W
Bead-Beating Homogenizer
Bead-Based Homogenizer
Ideal when high throughput is required, allowing many samples to be processed simultaneously (e.g., 96-well plates).
Zero tolerance for cross-contamination—each sample is handled in a sealed, independent tube.
Suitable when extracting heat-sensitive nucleic acids (such as RNA) or proteins; the instrument can be conveniently connected to a liquid-nitrogen system for low-temperature grinding.
Hammer-Type Homogenizer
Best suited for extremely tough, fibrous, or elastic samples, such as:
Plant materials: corn stalks, bark, roots and rhizomes
Animal tissues: cartilage, tendons, skin, muscle
