A PCR (Polymerase Chain Reaction) clean bench is a specialized type of clean bench designed specifically for PCR work, which requires a sterile and particulate-free environment to prevent contamination of samples and reagents. PCR clean benches provide a sterile workspace where PCR setup and manipulation can be performed under controlled conditions. They protect PCR reactions from airborne contaminants and minimize the risk of cross-contamination between samples. PCR clean benches typically feature HEPA-filtered laminar airflow that creates a sterile working environment by blowing filtered air across the work surface. This airflow helps to maintain a clean area where PCR tubes, reagents, and other materials can be handled without the risk of contamination. PCR clean benches are essential in molecular biology laboratories, diagnostic laboratories, and research facilities where PCR techniques are routinely used. They ensure the accuracy and reliability of PCR results by preventing contamination that could lead to false positives or erroneous data.

Limitations: While PCR clean benches provide a sterile environment for PCR setup and manipulation, they do not provide protection against aerosols or biological hazards. For work involving potentially infectious materials, a biosafety cabinet should be used instead.

Overall, PCR clean benches play a crucial role in ensuring the reliability and accuracy of PCR-based experiments by providing a controlled environment free from contaminants that could compromise results.